Skip to main content

Acute kidney failure

Overview

Acute kidney failure occurs when your kidneys suddenly become unable to filter waste products from your blood. When your kidneys lose their filtering ability, dangerous levels of wastes may accumulate, and your blood's chemical makeup may get out of balance.

Acute kidney failure — also called acute renal failure or acute kidney injury — develops rapidly, usually in less than a few days. Acute kidney failure is most common in people who are already hospitalized, particularly in critically ill people who need intensive care.

Acute kidney failure can be fatal and requires intensive treatment. However, acute kidney failure may be reversible. If you're otherwise in good health, you may recover normal or nearly normal kidney function.


Symptoms

Signs and symptoms of acute kidney failure may include:

  • Decreased urine output, although occasionally urine output remains normal
  • Fluid retention, causing swelling in your legs, ankles or feet
  • Shortness of breath
  • Fatigue
  • Confusion
  • Nausea
  • Weakness
  • Irregular heartbeat
  • Chest pain or pressure
  • Seizures or coma in severe cases

Sometimes acute kidney failure causes no signs or symptoms and is detected through lab tests done for another reason.

When to see a doctor

See your doctor immediately or seek emergency care if you have signs or symptoms of acute kidney failure.

Causes

Acute kidney failure can occur when:

  • You have a condition that slows blood flow to your kidneys
  • You experience direct damage to your kidneys
  • Your kidneys' urine drainage tubes (ureters) become blocked and wastes can't leave your body through your urine

Impaired blood flow to the kidneys

Diseases and conditions that may slow blood flow to the kidneys and lead to kidney injury include:

  • Blood or fluid loss
  • Blood pressure medications
  • Heart attack
  • Heart disease
  • Infection
  • Liver failure
  • Use of aspirin, ibuprofen (Advil, Motrin IB, others), naproxen sodium (Aleve, others) or related drugs
  • Severe allergic reaction (anaphylaxis)
  • Severe burns
  • Severe dehydration

Damage to the kidneys

These diseases, conditions and agents may damage the kidneys and lead to acute kidney failure:

  • Blood clots in the veins and arteries in and around the kidneys
  • Cholesterol deposits that block blood flow in the kidneys
  • Glomerulonephritis (gloe-mer-u-loe-nuh-FRY-tis), inflammation of the tiny filters in the kidneys (glomeruli)
  • Hemolytic uremic syndrome, a condition that results from premature destruction of red blood cells
  • Infection, such as with the virus that causes coronavirus disease 2019 (COVID-19)
  • Lupus, an immune system disorder causing glomerulonephritis
  • Medications, such as certain chemotherapy drugs, antibiotics and dyes used during imaging tests
  • Scleroderma, a group of rare diseases affecting the skin and connective tissues
  • Thrombotic thrombocytopenic purpura, a rare blood disorder
  • Toxins, such as alcohol, heavy metals and cocaine
  • Muscle tissue breakdown (rhabdomyolysis) that leads to kidney damage caused by toxins from muscle tissue destruction
  • Breakdown of tumor cells (tumor lysis syndrome), which leads to the release of toxins that can cause kidney injury

Urine blockage in the kidneys

Diseases and conditions that block the passage of urine out of the body (urinary obstructions) and can lead to acute kidney injury include:

  • Bladder cancer
  • Blood clots in the urinary tract
  • Cervical cancer
  • Colon cancer
  • Enlarged prostate
  • Kidney stones
  • Nerve damage involving the nerves that control the bladder
  • Prostate cancer

Risk factors

Acute kidney failure almost always occurs in connection with another medical condition or event. Conditions that can increase your risk of acute kidney failure include:

  • Being hospitalized, especially for a serious condition that requires intensive care
  • Advanced age
  • Blockages in the blood vessels in your arms or legs (peripheral artery disease)
  • Diabetes
  • High blood pressure
  • Heart failure
  • Kidney diseases
  • Liver diseases
  • Certain cancers and their treatments

Complications

Potential complications of acute kidney failure include:

  • Fluid buildup. Acute kidney failure may lead to a buildup of fluid in your lungs, which can cause shortness of breath.
  • Chest pain. If the lining that covers your heart (pericardium) becomes inflamed, you may experience chest pain.
  • Muscle weakness. When your body's fluids and electrolytes — your body's blood chemistry — are out of balance, muscle weakness can result.
  • Permanent kidney damage. Occasionally, acute kidney failure causes permanent loss of kidney function, or end-stage renal disease. People with end-stage renal disease require either permanent dialysis — a mechanical filtration process used to remove toxins and wastes from the body — or a kidney transplant to survive.
  • Death. Acute kidney failure can lead to loss of kidney function and, ultimately, death.

Prevention

Acute kidney failure is often difficult to predict or prevent. But you may reduce your risk by taking care of your kidneys. Try to:

  • Pay attention to labels when taking over-the-counter (OTC) pain medications. Follow the instructions for OTC pain medications, such as aspirin, acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, others). Taking too much of these medications may increase your risk of kidney injury. This is especially true if you have pre-existing kidney disease, diabetes or high blood pressure.
  • Work with your doctor to manage kidney and other chronic conditions. If you have kidney disease or another condition that increases your risk of acute kidney failure, such as diabetes or high blood pressure, stay on track with treatment goals and follow your doctor's recommendations to manage your condition.
  • Make a healthy lifestyle a priority. Be active; eat a sensible, balanced diet; and drink alcohol only in moderation — if at all.

Comments

Popular posts from this blog

Cold Urticaria

Overview Cold allergy or in medical terms called cold urticaria is the reaction of the skin to cold which causes itching to appear and the skin becomes reddish in color. The severity of cold allergy symptoms that appear on each person is different. Some people can lose consciousness, experience very low blood pressure, and even the worst can cause death. Ages are the age most often affected by cold allergies, but usually will disappear completely within a few years. Symptoms Usually cold allergy symptoms appear when the skin is exposed to cold water or cold weather (below 4 degrees Celsius). Cold allergies are also more at risk of appearing in conditions that are windy and damp. The following are some cold allergy symptoms that can occur. Hands feel swollen when holding cold objects. Itchy lesions appear on the area of ​​the skin exposed to cold air. The lips and throat feel swollen when eating cold food or drinks. Reddish skin. Allergic reactions are usually most seve

COVID-19 (coronavirus) Quarantine, Self-Isolation and Social Distancing

COVID-19 (coronavirus) quarantine, self-isolation and social distancing Learn the difference between quarantine and self-isolation amid the COVID-19 (coronavirus) pandemic — and why it matters. You've read about people self-quarantining, social distancing, or isolating themselves during the coronavirus disease 2019 (COVID-19) pandemic. You may be confused about the various terms and wonder what you should be doing. These terms describe approaches for limiting the spread of disease during epidemics and pandemics:   Social distancing.  Keeping space between yourself and other people outside your household to prevent the spread of disease. Quarantine.  Separating people and limiting movement of people who have or may have been exposed to the disease to see if they become ill. Isolation.  Separating people who are ill from others to keep the disease from spreading. Social distancing   You're likely practicing social distancing if there's ongoing community spre

Ways to fight coronavirus transmission at home

Ways to fight coronavirus transmission at home Used properly, most common household disinfectants will kill the virus that causes COVID-19. Doctors and researchers are gaining a greater understanding about the coronavirus disease 2019 (COVID-19) outbreak and how the virus can spread. Public health messages emphasize the importance of frequent, thorough hand-washing and social distancing to slow the spread of  COVID-19 .   You can also take steps in your home to keep the virus from spreading. No special supplies are required. You likely already have what you need. How is COVID-19 spread?   The virus that causes  COVID-19  can be spread by contact with someone who has  COVID-19 , as well as contact with surfaces or objects that person has touched. When someone with  COVID-19  sneezes or coughs, respiratory droplets are released into the air. Droplets typically don't travel far — no more than 6 feet (about 2 meters). The virus may stay on surfaces from hours to days.